M.phil., Ph.D

• Professor , 16 years , Maitreyi College

Genetics

Developmental Biology

Reproductive Biology

.Founding Member, Centre for Research (2020 till date)

Member, GEM/CPPP committee (2017 till date)

Managing Editor, Vantage Journal of Thematic Analysis (2020 till date)

Deputy Coordinator, Central Evaluation Centre, Maitreyi College (2017 till date)

Endocrine control of Phagocyte Functions in Freshwater Teleost Channa punctatus

Major Research Project

1. 2024-2027: Major Research Project funded by DST-SERB under Core Research Grant in 2024 entitled “ Novel hormone asprosin in teleost Channa punctata: Identification,
characterization and its impact on reproduction”.
 

2. 2017-2021: Major Research Project funded by DBT-BIO-Care "Understanding signaling mechanism of Inflammation in teleost Channa punctatus "
Minor Research Projects

1. 2024-2025: Annual Research Project entitled "Progesterone as a pollutant in the aquatic environment: Implications in immunity and survival of fish" funded by CFR, Maitreyi College

2. 2023-2024: Annual Research Project entitled "Purification of fish recombinant asprosin and study it’s role in fish reproduction in spotted snakehead Channa punctata" funded by CFR, Maitreyi College

2. 2020-2021: Annual Research Project entitled "Survey of alternative traditional medicines used for diabetes management and a preliminary comparative assessment of their antidiabetic and antioxidant properties"funded by CFR, Maitreyi College

3. Knowledge, Attitude and Practice of Contraception among Women(May2022-July 2022). Funded by CFR, Maitreyi College

 

.1. Human Reproductive Biology and Health . Pearson Publications

2. Fundamentals of Practical Genetics and Biotechnology. Platinum Publishers

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1. Sathoria P, Chuphal B, Rai U, Roy B. Asprosin regulates male reproduction in teleosts: an in vitro study in Channa punctata. J Endocrinol. 2024 ;263(3):e240146. doi: 10.1530/JOE-24-0146. PMID: 39302003.
2. Chuphal B, Sathoria P, Rai U, Roy B. Insights into Molecular characterization of NOD1-RIPK interaction and Transcriptional Modulation in Response to LPS in Spotted Snakehead, Channa punctata (Bloch, 1793). Fish Shellfish Immunol. 2024 :109916. doi: 10.1016/j.fsi.2024.109916. Epub ahead of print. PMID: 39307255.
3. Phartyal, R., Biswas, C., Sharma, S., Bhatia, J., Yadav, T.,  Roy B., and  Singh J. (2024). Age at Menarche among Girls in Government and Private Schools of Delhi,
   India and Its Association with Diet, Physical Activity and BMI. HEALTH AND POPULATION: PERSPECTIVES AND ISSUES, 47 (1), 1-11.
4. Chuphal, B., Sathoria, P., Rai, U., & Roy, B. (2024). Sexual dimorphism in NLR transcripts and its downstream signaling protein IL-1ꞵ in teleost Channa punctata (Bloch, 1793). Scientific Reports, 14(1), 1923.
5. Chuphal, B., Rai, U., & Roy, B. (2024). Exploring the possible role of estradiol in the regulation of reproductive phase-dependent expression of NOD-like receptors in female Channa punctata. Aquaculture International, 32(1), 709-724.
6. Chuphal, B., Sathoria, P., Rai, U., & Roy, B. (2023). Exploring the effect of dihydrotestosterone on nucleotide‐binding and oligomerization domain‐like receptor expression in spotted snakehead Channa punctata (Bloch 1793). Journal of Fish Biology, 103(6), 1476-1487.
7. Sathoria, P., Chuphal, B., Rai, U., & Roy, B. (2023). Molecular cloning, characterization and 3D modelling of spotted snakehead fbn1 C-terminal region encoding asprosin and expression analysis of fbn1. Scientific Reports, 13(1), 4470.
8. Chuphal, B., Sathoria, P., Rai, U., & Roy, B. (2023). Crosstalk between reproductive and immune systems: the teleostean perspective. Journal of Fish Biology, 102(2), 302-316.
9. Tripathy, G. D., Roy, B., & Yadav, M (2022). On the Idea of a University.Vantage: Journal of Thematic Analysis. Vol 3(2), 1-4.
10. Roy, B., Basak, R., & Rai, U. (2022). Impact of xenoestrogens on sex differentiation and reproduction in teleosts. Aquaculture and Fisheries, 7(5), 562-571.
11. Chuphal, B., Rai, U., & Roy, B. (2022). Teleost NOD-like receptors and their downstream signaling pathways: A brief review. Fish and shellfish immunology reports, 3, 100056.
12. Tripathy, G. D., Roy, B., & Yadav, M (2022). Vantage: Journal of Thematic Analysis. Vol 3(1), 1-6.
13. Sathoria, P & Roy, B. (2022). Sustainable food production through integrated rice-fish farming in India: a brief review. Renewable Agriculture and Food Systems. Vol 37, 527–535.
14.  Chuphal, B.,  Rai, U.,  Kumar, R., Roy, B. (2021).Molecular and functional characterization of spotted snakehead NOD1 with an emphasis on structural insights into iE-DAP binding motifs employing advanced bioinformatic tools. Journal of Biomolecular structure and Dynamics, Vol 39, 1-13.
15. Roy B, Yadav M, Sharma S, et al. (2021). Postmenopausal Symptoms and Management by Women in Delhi–NCR .Indian Journal of Gender Studies, 28, 262-275.
16. Roy, B., Singh, J., & Dewan, T (2020). A comparative study of antioxidant activity and total phenolic content of fresh juices of some common Indian fruits with their commercial counterparts. Current Science, 118, 300-304.
17. Singh, J., Roy, B. , Jaldhi., Mishra, S.,  & Garg R (2020). Post Harvest Treatment for Preserving Antioxidant Properties and Total Phenolic Content of Tomatoes and Litchis. Vantage: Journal of Thematic Analysis, Vol 1, 125-135.
18. Singh, J., Roy, B. Yadav, A.,  Siddiqui, S., Setia, A., Ramesh, R., Singh, K (2018). Cervical cancer awareness and HPV vaccine acceptability among females in Delhi: A cross-sectional study.  Indian Journal of Cancer. Vol 55: 233-237
19. Roy B., Singh J., Dayal G., Sunsunwal S., Yadav B., Bhardwaj C., Teotia A., (2017). Detection of harmful adulterants in milk supplied to Delhi, India. Current Science. Vol. 112: 2316-2320. Impact factor-0.843. ISSN: 0011-3891
20. J Singh, Roy B.,  G Dayal , S Sunsunwal, B Yadav, C Bhardwaj, A Teotia (2015). Detection of common adulterants in milk from Delhi and NCR. DU Journal of Undergraduate Research and Innovation.  Volume 1, Issue I. ISSN: 2395-2334
21. Roy B & Rai, U. (2010). Transcriptomic and non-transcriptomic signaling mechanisms of cortisol in fishes. J. Scientific Res. Vol. 54 (1 and 2): 83-88. ISSN : 0447-9483
22. Roy B & Rai, U. (2009) Genomic and non-genomic effect of cortisol on phagocytosis in freshwater teleost Channa punctatus: an in vitro study. Steroids Vol. 74(4-5): 449-55. ISSN: 0039-128X. Impact Factor -3.106
23.  Roy B., Singh, R,  Kumar, S and Rai, U. (2008). Diurnal variation in phagocytic activity of splenic phagocytes in freshwater teleost Channa punctatus: melatonin and its signaling mechanism. J. Endocrinology. 199: 469-478. ISSN 0022-0795. Impact factor- 4.498 
24. Roy B & Umesh Rai, (2007). Role of adrenoceptor-coupled second messenger system   in sympatho-adrenomedullary modulation of splenic macrophage functions in live fish Channa punctatus. General and Comparative Endocrinology. ISSN: 0016-6480. . Impact factor-2.821
25. Roy B & Umesh Rai, (2004). Dual mode of catecholamine action on splenic macrophage phagocytosis in wall lizard, Hemidactylus flaviviridis. Gen Comp. Endocrinol.136, 180-191. ISSN: 0016-6480 . Impact factor- 2.821
26. Roy B & Umesh Rai, (2003). Dose-related genomic and non-genomic action of catecholamines on splenic macrophage phagocytosis in wall lizard. Proceedings of 5th AOSCE  held at Nara Japan
27. Invited Chapters
28. Rai, U. and Roy, B. (2007). “Sex determination and differentiation in vertebrates”. Published by NISCAIR, CSIR for e-Book on Reproductive Biology
29. Kumar, S., Roy, B., Rai, U. (2010) Hormonal Regulation of Testicular Functions in Reptiles. In Hormones and Reproduction of Vertebrates Vol. 3, eds. Norris, D., Lopez, K. Academic Press (Elsevier). ISBN: 978-0-12-374930-7

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International:

• Equinox 2023: The Annual Interantional Conference on Research, Development and Social Transformation organized by Centre for Research, Maitreyi College held from 23-25th August, 2023
• Equinox 2022: The Annual Interantional Conference on Expanding Frontiers of Knowledge organized by Centre for Research, Maitreyi College held from 23-25th August, 2023
• Equinox 2021: The Annual Interantional Conference on Sustainable Agriculture organized by Centre for Research, Maitreyi College held from 12-14th August, 2021
• International Colloquium on “Regulatory Mechanisms underlying Behaviour, Physiology and Development” organized by Department of Zoology, University of Delhi from March 24-26, 2021.
• International Summit on Women in STEM organized by DBT, on 23rd January 2020.
• Conference on ICNPHH-2020 organized by Deshbandhu college , on 28th November, 2019
• Global Conference on Reproductive Health with focus on occupational, Environmental and Lifestyle Factors organized by ISSRF on 24rd February, 2019
• International Symposium on Ciliate Biology held at New Delhi from April 4th-6th, 2018
• 6th International Congress of the Asia and Oceania Society for Comparative Endocrinology (AOSCE) held at University of North Bengal, Siliguri from December 10-14, 2007
• XV International Congress of Comparative Endocrinology held at Boston, Massachusetts from May 22-27, 2005

National:

• National Seminar on Innovation in Higher Education through Public Private /partnership model organized by Clustal Innovation Centre, March 2023
• Assessment and Accreditation of best practices in higher educational institute organized by IQAC,Maitreyi College, November,  2019
• Trends in Life Sciences and Biotechnology institute organized by Department of Botany, Maitreyi College, February, 2019
• 2nd National Conference on ‘Environmental Concerns of 21st Century: Indian and Global Context’ organized by Zakir Hussain College, March 2018
• Interdisciplinarity: Prospects& Challenges organized by Maitreyi College, April 2017
• 2nd National Conference on ‘Environmental Concerns of 21st Century: Indian and Global Context’, 29-30th Mar.2017, organized by Zakir Husain Delhi College (Evening), University of Delhi.
• National Conference on Nanoscience-Opportunities and Challenges held at Department of Chemistry, Maitreyi College, University of Delhi from February 19-20, 2016
• National Symposium on Man-made diseases: an urban menace held at Zoology Department, Maitreyi College, University of Delhi from February   11-12, 2016.
• Symposium on Functional Biology: Comparative Aspects in conjunction with Second meeting of Indian Sub-continent Branch of the International Neuropeptide Society held at Department of Zoology, University of Lucknow from March 19-21, 2009.
• National Symposium on Comparative Endocrinology and Reproductive Physiology: Insights and Challenges held at Visva-Bharati, Santiniketan from November 26-28, 2007
• National Symposium on An Update of Reproductive Endocrinology: Novel and Applied Strategies held at Banaras Hindu University, Varanasi from February 26-28, 2007
• National Symposium on Current Trends in Comparative Endocrinology Impact of Molecular Biology and Biotechnology held at Nagpur from November 27-29, 2003
• XXI symposium of the Society for Reproductive Biology & Comparative Endocrinology held at Banaras Hindu University, Varanasi from February 10-13, 2003
• National Colloquium on Catfish Physiology held at Banaras Hindu University, Varanasi from November 19-20, 2002

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Invited Lectures and Resource Person in Conference/Workshop

1. Exploring the modulation of immune functions by the reproductive system: Insights from teleosts. International Conference on Endocrinology, Metabolism and Reproduction: Exploring New Frontiers organized by Department of Zoology, University of Jammu , October 22-25th, 2024.
2. Shifting Paradigms of Education: Relevance To Self Reliance in Modern India. International Symposium on Philosophy and Science as a New Educational Paradigm organized by Kuruom School of Advanced Sciences, Lucknow, 2024
3. Research Methodology. Workshop on Research Methodology organized by Centre for Research, Maitreyi College, 2023
4. Role of Ethics in Life Sciences. Redefining ethics in the era of digitization: from theory to practice organized by Teaching Learning Centre, Ramanujan College, 2022
5. Data Presentation: Powerpoint, poster, Jam. Certificate Course on ICT in digital learning and data management organized by Maitreyi College, 2022
6. Poster Presentation and PowerPoint Presentation. National Workshop for Beginners, “Web Search, Data Analysis & Presentation Tools”. Organized by Maitreyi College, 2020.
7. Exciting Journeys: Ideas to execution. Organized by DBT-Biocare Conclave, 2019

7. Relevance of Extramural Grant for Research in Undergraduate College Setup. Assessment and Accreditation of best practices in higher educational institute, Organized by IQAC, Maitreyi College, 2019.

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My research is focused primarily on the endocrine regulation of the innate immune system of teleost. We have elucidated the genomic action of catecholamines and the non-genomic action of cortisol in the regulation of innate immunity for the first time in non-mammalian vertebrates. At present, my group is working on the intracellular pattern recognition receptors namely Nod-like receptors in teleost. We successfully demonstrated reproductive-phase-dependent expression of NOD-like receptors and sex-dependent variation in inflammatory responses in teleost, again a novel observation in non-mammalian vertebrates.

We are the first research group globally to successfully clone and characterize the novel hormone asprosin in teleosts. At present our group is working on understanding the physiological aspect of this novel adipokine in teleost.

In recent years I have been also working in the area of public health with my undergraduate students. We have conducted many survey-based research on menopause, menarche, contraception, and cervical cancer awareness. One of our papers on milk adulteration in Delhi-NCR published in Current Science was widely covered in National newspapers such as the Hindu.